Four haloed figures and two kneeling figures before a city, with winged figures in the sky
The artwork shows four standing male figures and two kneeling figures in the foreground, set against a landscape with a city and mountains, beneath a sky with flying winged figures. The upper portion of the image features a light blue sky with scattered white clouds. In the upper left and right corners, groups of winged, robed figures, likely angels, are depicted flying. Some appear to hold thin lines or bows. Below the winged figures, a detailed cityscape with numerous buildings, towers, and walls extends across the middle ground, appearing to be situated between hills. Rolling hills and mountains rise in the distance behind the city. Two tall, slender dark green trees, possibly cypress trees, stand prominently in the center, positioned between the standing figures. On the far left, a balding man with a halo stands, dressed in a dark brown habit adorned with white flowers on his chest. He holds a closed dark book in his left hand. The inscription "SANTVS NICHOLAVS DETOLENTINO" arcs above his head. Next to him, a young man with a short beard and halo wears a purple tunic and a yellow cloak draped over his shoulder. He holds a tall, gnarled staff in his right hand, and his right leg is exposed, revealing a dark mark on his exposed right thigh. The inscription "SANCTVS ROCHVS" arcs above his head. To the right of the trees, a youthful figure with curly light brown hair and a halo stands in a red and dark green tunic with white trim. He holds several arrows in his left hand and a green palm frond in his right. The inscription "SANCTVS SEBASTIANVS" arcs above his head. On the far right, an older, balding man with a halo wears a light brown habit. He holds an open book in his left hand, displaying text. His right hand is raised, with the index finger pointing upwards. The inscription "SANTVS BERNARDINVS" arcs above his head. The text on his book reads: "PICEA ANVPE SAPIEN TIA VITA VIRTVS VERITAS". At the lower left, a male figure kneels in profile, facing right, with hands clasped in prayer. He wears a dark robe and a red cap. At the lower right, a female figure kneels in profile, facing left, with hands clasped in prayer. She wears a dark dress and a white head covering. A white inscription on a dark band runs horizontally across the lower center, positioned between the feet of the standing figures: "QVESTA TAVOLA E FACTA FARE PER DEVOZIONE DI SANCTO SEBASTIANO E SANCTO ROCHO PER LA PESTILENTIA DA FRATE BARTOLOMEO DI GIOVANNI DA CASTIGLION FIORENTINO PRIORE DI QVESTO MONASTERO DI SANCTO AGOSTINO DI SAN GIMIGNANO". The ground is a light, tiled surface.